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Steered molecular dynamic simulations of conformational lock of Cu, Zn-superoxide dismutase
The conformational lock was a bio-thermodynamic theory to explain the characteristics of interfaces in oligomeric enzymes and their effects on catalytic activity. The previous studies on superoxide dismutases (Cu, Zn-SODs) showed that the dimeric structure contributed to the high catalytic efficienc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416402/ https://www.ncbi.nlm.nih.gov/pubmed/30867507 http://dx.doi.org/10.1038/s41598-019-40892-0 |