Widespread PERK-dependent repression of ER targets in response to ER stress

The UPR (Unfolded Protein Response) is a well-orchestrated response to ER protein folding and processing overload, integrating both transcriptional and translational outputs. Its three arms in mammalian cells, the PERK translational response arm, together with the ATF6 and IRE1-XBP1-mediated transcr...

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Detalles Bibliográficos
Autores principales: Gonen, Nir, Sabath, Niv, Burge, Christopher B., Shalgi, Reut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416471/
https://www.ncbi.nlm.nih.gov/pubmed/30867432
http://dx.doi.org/10.1038/s41598-019-38705-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416471/
https://www.ncbi.nlm.nih.gov/pubmed/30867432
http://dx.doi.org/10.1038/s41598-019-38705-5

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