Anti-cancer Effects of a Chemically Modified miR-143 on Bladder Cancer by Either Systemic or Intravesical Treatment

We developed a novel chemically modified miR-143 (miR-143#12), and with it we investigated the contribution of miR-143 to the pathogenesis of bladder cancer (BC), in which miR-143 is extremely downregulated. Since miR-143 silenced K-RAS and RAS effector-signaling molecules Erk and Akt, we performed...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Yuki, Taniguchi, Kohei, Tsujino, Takuya, Heishima, Kazuki, Inamoto, Teruo, Takai, Tomoaki, Minami, Koichiro, Azuma, Haruhito, Miyata, Kanjiro, Hayashi, Kotaro, Kataoka, Kazunori, Akao, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416526/
https://www.ncbi.nlm.nih.gov/pubmed/30911586
http://dx.doi.org/10.1016/j.omtm.2019.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416526/
https://www.ncbi.nlm.nih.gov/pubmed/30911586
http://dx.doi.org/10.1016/j.omtm.2019.02.005

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