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An increase in intracellular p62/NBR1 and persistence of Burkholderia mallei and B. pseudomallei in infected mice linked to autophagy deficiency

INTRODUCTION: Burkholderia mallei (B. mallei) and Burkholderia pseudomallei (B. pseudomallei), causative agents of glanders and melioidosis, respectively, are invasive intracellular pathogens that actively multiply in phagocytic and non‐phagocytic cells. Activation of cell‐autonomous autophagy mecha...

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Detalles Bibliográficos
Autores principales: Saikh, Kamal U., Dankmeyer, Jennifer L., Zeng, Xiankun, Ulrich, Robert G., Amemiya, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416765/
https://www.ncbi.nlm.nih.gov/pubmed/30569531
http://dx.doi.org/10.1002/iid3.239