miR-29b-3p regulated osteoblast differentiation via regulating IGF-1 secretion of mechanically stimulated osteocytes

BACKGROUND: Mechanical loading is an essential factor for bone formation. A previous study indicated that mechanical tensile strain of 2500 microstrain (με) at 0.5 Hz for 8 h promoted osteogenesis and corresponding mechanoresponsive microRNAs (miRs) were identified in osteoblasts. However, in osteoc...

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Detalles Bibliográficos
Autores principales: Zeng, Qiangcheng, Wang, Yang, Gao, Jie, Yan, Zhixiong, Li, Zhenghua, Zou, Xianqiong, Li, Yanan, Wang, Jiahui, Guo, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416934/
https://www.ncbi.nlm.nih.gov/pubmed/30915127
http://dx.doi.org/10.1186/s11658-019-0136-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416934/
https://www.ncbi.nlm.nih.gov/pubmed/30915127
http://dx.doi.org/10.1186/s11658-019-0136-2

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