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MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12

BACKGROUND: Cancer stem cells (CSCs) play an important role in the development of pancreatic cancer. We previously showed that the microRNA miR-137 is downregulated in clinical samples of pancreatic cancer, and its expression negatively regulates the proliferation and invasiveness of pancreatic canc...

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Detalles Bibliográficos
Autores principales: He, Zhiwei, Guo, Xingjun, Tian, She, Zhu, Changhao, Chen, Shiyu, Yu, Chao, Jiang, Jianxin, Sun, Chengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416947/
https://www.ncbi.nlm.nih.gov/pubmed/30866999
http://dx.doi.org/10.1186/s13046-019-1105-3