Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy

Growing evidences are suggesting that extra-long genes in mammals are vulnerable for full-gene length transcription and dysregulation of long genes is a mechanism underlying human genetic disorders. How long-distance transcription is achieved is a fundamental question to be elucidated. In previous s...

Descripción completa

Detalles Bibliográficos
Autores principales: Hosokawa, Motoyasu, Takeuchi, Akihide, Tanihata, Jun, Iida, Kei, Takeda, Shin'ichi, Hagiwara, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416966/
https://www.ncbi.nlm.nih.gov/pubmed/30870781
http://dx.doi.org/10.1016/j.isci.2019.02.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416966/
https://www.ncbi.nlm.nih.gov/pubmed/30870781
http://dx.doi.org/10.1016/j.isci.2019.02.023

Ejemplares similares