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Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy
Growing evidences are suggesting that extra-long genes in mammals are vulnerable for full-gene length transcription and dysregulation of long genes is a mechanism underlying human genetic disorders. How long-distance transcription is achieved is a fundamental question to be elucidated. In previous s...
Autores principales: | Hosokawa, Motoyasu, Takeuchi, Akihide, Tanihata, Jun, Iida, Kei, Takeda, Shin'ichi, Hagiwara, Masatoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416966/ https://www.ncbi.nlm.nih.gov/pubmed/30870781 http://dx.doi.org/10.1016/j.isci.2019.02.023 |
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