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Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

BACKGROUND: Senescent cells exert a significant influence over their surrounding cellular environment. Senescent chondrocytes (SnChos) were found to be accumulated in degenerated cartilage present in joints affected by osteoarthritis. The influence of SnChos on exogenously transplanted stem cells ha...

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Detalles Bibliográficos
Autores principales: Cao, Xu, Luo, Pan, Huang, Junjie, Liang, Chi, He, Jinshen, Wang, Zili, Shan, Dongyong, Peng, Cheng, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416972/
https://www.ncbi.nlm.nih.gov/pubmed/30867061
http://dx.doi.org/10.1186/s13287-019-1193-1