DSab-origin: a novel IGHD sensitive VDJ mapping method and its application on antibody response after influenza vaccination

BACKGROUND: Functional antibody genes are often assembled by VDJ recombination and then diversified by somatic hypermutation. Identifying the combination of sourcing germline genes is critical to understand the process of antibody maturation, which may facilitate the diagnostics and rapid generation...

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Detalles Bibliográficos
Autores principales: Zhang, Qingchen, Zhang, Lu, Zhou, Chen, Yang, Yiyan, Yin, Zuojing, Wu, Dingfeng, Tang, Kailin, Cao, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417009/
https://www.ncbi.nlm.nih.gov/pubmed/30871465
http://dx.doi.org/10.1186/s12859-019-2715-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417009/
https://www.ncbi.nlm.nih.gov/pubmed/30871465
http://dx.doi.org/10.1186/s12859-019-2715-7

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