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DSab-origin: a novel IGHD sensitive VDJ mapping method and its application on antibody response after influenza vaccination
BACKGROUND: Functional antibody genes are often assembled by VDJ recombination and then diversified by somatic hypermutation. Identifying the combination of sourcing germline genes is critical to understand the process of antibody maturation, which may facilitate the diagnostics and rapid generation...
Autores principales: | Zhang, Qingchen, Zhang, Lu, Zhou, Chen, Yang, Yiyan, Yin, Zuojing, Wu, Dingfeng, Tang, Kailin, Cao, Zhiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417009/ https://www.ncbi.nlm.nih.gov/pubmed/30871465 http://dx.doi.org/10.1186/s12859-019-2715-7 |
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