HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis

Lung interstitial CD4+ T cells are critical for protection against pulmonary infections, but the fate of this population during HIV-1 infection is not well described. We studied CD4+ T cells in the setting of HIV-1 infection in human lung tissue, humanized mice, and a Mycobacterium tuberculosis (Mtb...

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Detalles Bibliográficos
Autores principales: Corleis, Björn, Bucsan, Allison N., Deruaz, Maud, Vrbanac, Vladimir D., Lisanti-Park, Antonella C., Gates, Samantha J., Linder, Alice H., Paer, Jeffrey M., Olson, Gregory S., Bowman, Brittany A., Schiff, Abigail E., Medoff, Benjamin D., Tager, Andrew M., Luster, Andrew D., Khader, Shabaana A., Kaushal, Deepak, Kwon, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417097/
https://www.ncbi.nlm.nih.gov/pubmed/30726727
http://dx.doi.org/10.1016/j.celrep.2019.01.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417097/
https://www.ncbi.nlm.nih.gov/pubmed/30726727
http://dx.doi.org/10.1016/j.celrep.2019.01.021

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