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Integrating germline and somatic variation information using genomic data for the discovery of biomarkers in prostate cancer
BACKGROUND: Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading cause of cancer-related deaths among men in the United States. High-throughput genotyping has enabled discovery of germline genetic susceptibility variants (herein referred to as germline mutations) asso...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417124/ https://www.ncbi.nlm.nih.gov/pubmed/30871495 http://dx.doi.org/10.1186/s12885-019-5440-8 |