Design and analysis of stably integrated reporters for inducible transgene expression in human T cells and CAR NK-cell lines

BACKGROUND: Cytotoxic activity of T- and NK-cells can be efficiently retargeted against cancer cells using chimeric antigen receptors (CARs) and rTCRs. In the context of solid cancers, use of armored CAR T- and NK cells secreting additional anti-cancer molecules such as cytokines, chemokines, antibo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulemzin, Sergey V., Matvienko, Daria A., Sabirov, Artur H., Sokratyan, Arpine M., Chernikova, Daria S., Belovezhets, Tatyana N., Chikaev, Anton N., Taranin, Aleksandr V., Gorchakov, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417161/
https://www.ncbi.nlm.nih.gov/pubmed/30871576
http://dx.doi.org/10.1186/s12920-019-0489-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417161/
https://www.ncbi.nlm.nih.gov/pubmed/30871576
http://dx.doi.org/10.1186/s12920-019-0489-4

Ejemplares similares