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Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metabolite of ellagic acid, has been reported to exert anti-inflammato...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417212/ https://www.ncbi.nlm.nih.gov/pubmed/30871577 http://dx.doi.org/10.1186/s12974-019-1450-3 |