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GSK-3β protects fetal oocytes from premature death via modulating TAp63 expression in mice
BACKGROUND: Female mammals have a limited reproductive lifespan determined by the size of the primordial follicle pool established perinatally. Over two thirds of fetal oocytes are abolished via programmed cell death during early folliculogenesis. However, the underlying mechanisms governing fetal o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417224/ https://www.ncbi.nlm.nih.gov/pubmed/30866939 http://dx.doi.org/10.1186/s12915-019-0641-9 |