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GSK-3β protects fetal oocytes from premature death via modulating TAp63 expression in mice

BACKGROUND: Female mammals have a limited reproductive lifespan determined by the size of the primordial follicle pool established perinatally. Over two thirds of fetal oocytes are abolished via programmed cell death during early folliculogenesis. However, the underlying mechanisms governing fetal o...

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Detalles Bibliográficos
Autores principales: Wen, Jia, Yan, Hao, He, Meina, Zhang, Tuo, Mu, Xinyi, Wang, Haibin, Zhang, Hua, Xia, Guoliang, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417224/
https://www.ncbi.nlm.nih.gov/pubmed/30866939
http://dx.doi.org/10.1186/s12915-019-0641-9