Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits

BACKGROUND: Microglia play a central role in most neurological disorders, but the impact of microgliosis on brain environment and clinical functions is not fully understood. Mice lacking multifunctional protein-2 (MFP2), a pivotal enzyme in peroxisomal β-oxidation, develop a fatal disorder character...

Descripción completa

Detalles Bibliográficos
Autores principales: Beckers, Lien, Geric, Ivana, Stroobants, Stijn, Beel, Sander, Van Damme, Philip, D’Hooge, Rudi, Baes, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417251/
https://www.ncbi.nlm.nih.gov/pubmed/30866963
http://dx.doi.org/10.1186/s12974-019-1442-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417251/
https://www.ncbi.nlm.nih.gov/pubmed/30866963
http://dx.doi.org/10.1186/s12974-019-1442-3

Ejemplares similares