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The hyper-activation of transcriptional enhancers in breast cancer

BACKGROUND: Activation of transcription enhancers, especially super-enhancers, is one of the critical epigenetic features of tumorigenesis. However, very few studies have systematically identified the enhancers specific in cancer tissues. METHODS: Here, we studied the change of histone modifications...

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Detalles Bibliográficos
Autores principales: Li, Qing-Lan, Wang, Dan-Ya, Ju, Lin-Gao, Yao, Jie, Gao, Chuan, Lei, Pin-Ji, Li, Lian-Yun, Zhao, Xiao-Lu, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417266/
https://www.ncbi.nlm.nih.gov/pubmed/30867030
http://dx.doi.org/10.1186/s13148-019-0645-x