Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements

The glucocorticoid receptor (GR), a hormone-activated transcription factor, binds to a myriad of genomic binding sites yet seems to regulate a much smaller number of genes. Genome-wide analysis of GR binding and gene regulation has shown that the likelihood of GR-dependent regulation increases with...

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Detalles Bibliográficos
Autores principales: Thormann, Verena, Glaser, Laura V, Rothkegel, Maika C, Borschiwer, Marina, Bothe, Melissa, Fuchs, Alisa, Meijsing, Sebastiaan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417287/
https://www.ncbi.nlm.nih.gov/pubmed/30867223
http://dx.doi.org/10.26508/lsa.201800283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417287/
https://www.ncbi.nlm.nih.gov/pubmed/30867223
http://dx.doi.org/10.26508/lsa.201800283

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