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Recurrent herpes simplex virus-1 infection induces hallmarks of neurodegeneration and cognitive deficits in mice

Herpes simplex virus type 1 (HSV-1) is a DNA neurotropic virus, usually establishing latent infections in the trigeminal ganglia followed by periodic reactivations. Although numerous findings suggested potential links between HSV-1 and Alzheimer’s disease (AD), a causal relation has not been demonst...

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Detalles Bibliográficos
Autores principales: De Chiara, Giovanna, Piacentini, Roberto, Fabiani, Marco, Mastrodonato, Alessia, Marcocci, Maria Elena, Limongi, Dolores, Napoletani, Giorgia, Protto, Virginia, Coluccio, Paolo, Celestino, Ignacio, Li Puma, Domenica Donatella, Grassi, Claudio, Palamara, Anna Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417650/
https://www.ncbi.nlm.nih.gov/pubmed/30870531
http://dx.doi.org/10.1371/journal.ppat.1007617