A nonsense mutant of the hepatitis B virus large S protein antagonizes multiple tumor suppressor pathways through c-Jun activation domain-binding protein1

Hepatitis B virus (HBV) is a major cause of hepatocellular carcinoma (HCC). Previous studies have identified recurrent nonsense mutations in the HBV large S (LHBs) gene from the liver from HBV core antigen-positive HCC patients. These nonsense mutants have been shown to be oncogenic in mouse xenogra...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiu, Shu-Yi, Chung, Hsiang-Ju, Chen, Ya-Ting, Huang, Min-Syuan, Huang, Chien-Chih, Huang, Shiu-Feng, Matsuura, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417713/
https://www.ncbi.nlm.nih.gov/pubmed/30870427
http://dx.doi.org/10.1371/journal.pone.0208665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417713/
https://www.ncbi.nlm.nih.gov/pubmed/30870427
http://dx.doi.org/10.1371/journal.pone.0208665

Ejemplares similares