Cargando…

A nonsense mutant of the hepatitis B virus large S protein antagonizes multiple tumor suppressor pathways through c-Jun activation domain-binding protein1

Hepatitis B virus (HBV) is a major cause of hepatocellular carcinoma (HCC). Previous studies have identified recurrent nonsense mutations in the HBV large S (LHBs) gene from the liver from HBV core antigen-positive HCC patients. These nonsense mutants have been shown to be oncogenic in mouse xenogra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiu, Shu-Yi, Chung, Hsiang-Ju, Chen, Ya-Ting, Huang, Min-Syuan, Huang, Chien-Chih, Huang, Shiu-Feng, Matsuura, Isao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417713/ https://www.ncbi.nlm.nih.gov/pubmed/30870427 http://dx.doi.org/10.1371/journal.pone.0208665

Ejemplares similares

Selective antagonism of cJun for cancer therapy
por: Brennan, Andrew, et al.
Publicado: (2020)

Fuse binding protein antagonizes the transcription activity of tumor suppressor protein p53
por: Dixit, Updesh, et al.
Publicado: (2014)

Identification of Transforming Hepatitis B Virus S Gene Nonsense Mutations Derived from Freely Replicative Viruses in Hepatocellular Carcinoma
por: Huang, Shiu-Feng, et al.
Publicado: (2014)

Synergistic Rescue of Nonsense Mutant Tumor Suppressor p53 by Combination Treatment with Aminoglycosides and Mdm2 Inhibitors
por: Zhang, Meiqiongzi, et al.
Publicado: (2018)

Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein
por: Lo, Yu-Sheng, et al.
Publicado: (2013)

Therapeutic promise of engineered nonsense suppressor tRNAs
por: Porter, Joseph J., et al.
Publicado: (2021)

Rational design of an orthogonal tryptophanyl nonsense suppressor tRNA
por: Hughes, Randall A., et al.
Publicado: (2010)

Whole genome sequencing data and analyses of the underlying SUP35 transcriptional regulation for a Saccharomyces cerevisiae nonsense suppressor mutant
por: Matveenko, Andrew G., et al.
Publicado: (2019)

SUZ domain–containing proteins have multiple effects on nonsense-mediated decay target transcripts
por: Halbout, Mathias, et al.
Publicado: (2023)

HTLV-3 and HTLV-4 antisense proteins activate JunB-, c-Jun- and JunD-dependent transcription
por: Larocque, Émilie, et al.
Publicado: (2011)

Pleiotropic tumor suppressor functions of WWOX antagonize metastasis
por: Khawaled, Saleh, et al.
Publicado: (2020)

Possible Role of MADS AFFECTING FLOWERING 3 and B-BOX DOMAIN PROTEIN 19 in Flowering Time Regulation of Arabidopsis Mutants with Defects in Nonsense-Mediated mRNA Decay
por: Nasim, Zeeshan, et al.
Publicado: (2017)

DCMP: database of cancer mutant protein domains
por: Emerson, Isaac Arnold, et al.
Publicado: (2021)

Making sense of nonsense: the evolution of selenocysteine usage in proteins
por: Copeland, Paul R
Publicado: (2005)

The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation
por: Weidmann, Chase A., et al.
Publicado: (2014)

Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae
por: Moskalenko, Svetlana E, et al.
Publicado: (2003)

Nonsense Mediated Decay Resistant Mutations Are a Source of Expressed Mutant Proteins in Colon Cancer Cell Lines with Microsatellite Instability
por: Williams, David S., et al.
Publicado: (2010)

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1
por: Chang, Yi-Fang, et al.
Publicado: (2014)

Prediction of Cancer Proteins by Integrating Protein Interaction, Domain Frequency, and Domain Interaction Data Using Machine Learning Algorithms
por: Huang, Chien-Hung, et al.
Publicado: (2015)

A Domain Responsible for the Transformation Suppressor Activity in Krev‐1 Protein
por: Kitayama, Hitoshi, et al.
Publicado: (1990)

Detection of Rare Methyl-CpG Binding Protein 2 Gene Missense Mutations in Patients With Schizophrenia
por: Chen, Chia-Hsiang, et al.
Publicado: (2020)

Correction: Nonsense Mediated Decay Resistant Mutations Are a Source of Expressed Mutant Proteins in Colon Cancer Cell Lines with Microsatellite Instability
por: Williams, David S., et al.
Publicado: (2011)

Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC
por: Wang, Zi, et al.
Publicado: (2015)

Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae
por: Chabelskaya, Svetlana, et al.
Publicado: (2007)

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment
por: Riesenberg, Stefanie, et al.
Publicado: (2015)

Mitogen-activated Protein Kinase Kinase Antagonized Fas-associated Death Domain Protein–mediated Apoptosis by Induced FLICE-inhibitory Protein Expression
por: Yeh, Jung-Hua, et al.
Publicado: (1998)

The Relevance of Women's Diseases, Jun Activation-domain Binding Protein 1 (JAB1) and p27(kip1)
por: Kim, Mijin, et al.
Publicado: (2016)

Prognostic role of c‐Jun activation domain‐binding protein‐1 in cancer: A systematic review and meta‐analysis
por: Shi, Deyao, et al.
Publicado: (2021)

B7-H3 Promotes Prostate Cancer Progression in Mice by Antagonizing Myeloid-Derived Suppressor Cell Apoptosis
por: Zhou, Yunfen, et al.
Publicado: (2020)

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC
por: Wang, Zi, et al.
Publicado: (2019)

Jun Dimerization Protein 2 Controls Senescence and Differentiation via Regulating Histone Modification
por: Huang, Yu-Chang, et al.
Publicado: (2011)

Biochemical Characterization of the Phosphatase Domain of the Tumor Suppressor PH Domain Leucine-Rich Repeat Protein Phosphatase
por: Sierecki, Emma, et al.
Publicado: (2014)

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits
por: Ho, Wan Yun, et al.
Publicado: (2021)

Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism
por: Huang, Su-Hua, et al.
Publicado: (2017)

Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine
por: Palomar-Siles, Mireia, et al.
Publicado: (2022)

Incorporating Amino Acids Composition and Functional Domains for Identifying Bacterial Toxin Proteins
por: Su, Min-Gang, et al.
Publicado: (2014)

BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathways
por: Chen, Xu-Xiao, et al.
Publicado: (2018)

Antagonism of Innate Immunity by Paramyxovirus Accessory Proteins
por: Chambers, Raychel, et al.
Publicado: (2009)

c-Jun N-terminal kinase inhibitor favors transforming growth factor-β to antagonize hepatitis B virus X protein-induced cell growth promotion in hepatocellular carcinoma
por: WU, YAN-HUI, et al.
Publicado: (2016)

Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants
por: Liu, Yuanli, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4cuj74klb6j0s0v4954a24o5t5