QSAR modelling of a large imbalanced aryl hydrocarbon activation dataset by rational and random sampling and screening of 80,086 REACH pre-registered and/or registered substances

The Aryl hydrocarbon receptor (AhR) plays important roles in many normal and pathological physiological processes, including endocrine homeostasis, foetal development, cell cycle regulation, cellular oxidation/antioxidation, immune regulation, metabolism of endogenous and exogenous substances, and c...

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Detalles Bibliográficos
Autores principales: Klimenko, Kyrylo, Rosenberg, Sine A., Dybdahl, Marianne, Wedebye, Eva B., Nikolov, Nikolai G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417725/
https://www.ncbi.nlm.nih.gov/pubmed/30870500
http://dx.doi.org/10.1371/journal.pone.0213848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417725/
https://www.ncbi.nlm.nih.gov/pubmed/30870500
http://dx.doi.org/10.1371/journal.pone.0213848

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