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Defining the role of NG2-expressing cells in experimental models of multiple sclerosis. A biofunctional analysis of the neurovascular unit in wild type and NG2 null mice

During experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis associated with blood-brain barrier (BBB) disruption, oligodendrocyte precursor cells (OPCs) overexpress proteoglycan nerve/glial antigen 2 (NG2), proliferate, and make contacts with the microvessel wall. To explo...

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Detalles Bibliográficos
Autores principales: Girolamo, Francesco, Errede, Mariella, Longo, Giovanna, Annese, Tiziana, Alias, Carlotta, Ferrara, Giovanni, Morando, Sara, Trojano, Maria, Kerlero de Rosbo, Nicole, Uccelli, Antonio, Virgintino, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417733/
https://www.ncbi.nlm.nih.gov/pubmed/30870435
http://dx.doi.org/10.1371/journal.pone.0213508