Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival

Natural killer (NK) cells have increasingly become a target of interest for immunotherapies1. NK cells express killer immunoglobulin-like receptors (KIRs), which play a vital role in immune response to tumors by detecting cellular abnormalities. The genomic region encoding the 16 KIR genes displays...

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Detalles Bibliográficos
Autores principales: Pyke, Rachel M., Genolet, Raphael, Harari, Alexandre, Coukos, George, Gfeller, David, Carter, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417817/
https://www.ncbi.nlm.nih.gov/pubmed/30864318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417817/
https://www.ncbi.nlm.nih.gov/pubmed/30864318

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