Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1)

Schwann cells are integral components of vertebrate neuromuscular synapses; in their absence, pre-synaptic nerve terminals withdraw from post-synaptic muscles, leading to muscle denervation and synapse loss at the developing neuromuscular junction (NMJ). Here, we report a rescue of muscle denervatio...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Sugiura, Yoshie, Chen, Fujun, Lee, Kuo-Fen, Ye, Qiaohong, Lin, Weichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417856/
https://www.ncbi.nlm.nih.gov/pubmed/30870432
http://dx.doi.org/10.1371/journal.pgen.1007857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417856/
https://www.ncbi.nlm.nih.gov/pubmed/30870432
http://dx.doi.org/10.1371/journal.pgen.1007857

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