Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation

Ligand-dependent oligomerization of receptor tyrosine kinases (RTKs) results in their activation through highly specific conformational changes in the extracellular and intracellular receptor domains. These conformational changes are unique for each RTK sub-family, limiting cross-activation between...

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Detalles Bibliográficos
Autores principales: Frazier, Nicole Michael, Brand, Toni, Gordan, John D., Grandis, Jennifer, Jura, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417953/
https://www.ncbi.nlm.nih.gov/pubmed/30390071
http://dx.doi.org/10.1038/s41388-018-0537-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417953/
https://www.ncbi.nlm.nih.gov/pubmed/30390071
http://dx.doi.org/10.1038/s41388-018-0537-0

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