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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes
More than 1,100 genetic loci have been correlated with drug response outcomes but disproportionately few have been translated into clinical practice. One explanation for the low rate of clinical implementation is that the majority of associated variants may be in linkage disequilibrium (LD) with the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417988/ https://www.ncbi.nlm.nih.gov/pubmed/30214008 http://dx.doi.org/10.1038/s41397-018-0048-y |