Booster Vaccination With GVGH Shigella sonnei 1790GAHB GMMA Vaccine Compared to Single Vaccination in Unvaccinated Healthy European Adults: Results From a Phase 1 Clinical Trial

The investigational Shigella sonnei vaccine (1790GAHB) based on GMMA (generalized modules for membrane antigens) is immunogenic, with an acceptable safety profile in adults. However, pre-vaccination anti-S. sonnei lipopolysaccharide (LPS) antibody levels seemed to impact vaccine-related immune respo...

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Detalles Bibliográficos
Autores principales: Launay, Odile, Ndiaye, Augustin G. W., Conti, Valentino, Loulergue, Pierre, Sciré, Antonella Silvia, Landre, Anais Maugard, Ferruzzi, Pietro, Nedjaai, Naouel, Schütte, Lena Dorothee, Auerbach, Joachim, Marchetti, Elisa, Saul, Allan, Martin, Laura B., Podda, Audino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418009/
https://www.ncbi.nlm.nih.gov/pubmed/30906291
http://dx.doi.org/10.3389/fimmu.2019.00335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418009/
https://www.ncbi.nlm.nih.gov/pubmed/30906291
http://dx.doi.org/10.3389/fimmu.2019.00335

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