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C5b9 Deposition in Glomerular Capillaries Is Associated With Poor Kidney Allograft Survival in Antibody-Mediated Rejection

C4d deposition in peritubular capillaries (PTC) reflects complement activation in antibody-mediated rejection (ABMR) of kidney allograft. However, its association with allograft survival is controversial. We hypothesized that capillary deposition of C5b9—indicative of complement-mediated injury—is a...

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Detalles Bibliográficos
Autores principales: Goutaudier, Valentin, Perrochia, Hélène, Mucha, Simon, Bonnet, Marie, Delmas, Sylvie, Garo, Florian, Garrigue, Valérie, Lepreux, Sébastien, Pernin, Vincent, Serre, Jean-Emmanuel, Szwarc, Ilan, Merville, Pierre, Ramounau-Pigot, Annie, René, Céline, Visentin, Jonathan, Morgan, Bryan Paul, Frémeaux-Bacchi, Véronique, Mourad, Georges, Couzi, Lionel, Le Quintrec, Moglie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418012/
https://www.ncbi.nlm.nih.gov/pubmed/30906289
http://dx.doi.org/10.3389/fimmu.2019.00235