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Quantitative Systems Pharmacological Analysis of Drugs of Abuse Reveals the Pleiotropy of Their Targets and the Effector Role of mTORC1

Existing treatments against drug addiction are often ineffective due to the complexity of the networks of protein-drug and protein-protein interactions (PPIs) that mediate the development of drug addiction and related neurobiological disorders. There is an urgent need for understanding the molecular...

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Detalles Bibliográficos
Autores principales: Pei, Fen, Li, Hongchun, Liu, Bing, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418047/
https://www.ncbi.nlm.nih.gov/pubmed/30906261
http://dx.doi.org/10.3389/fphar.2019.00191