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Telmisartan attenuates kidney apoptosis and autophagy-related protein expression levels in an intermittent hypoxia mouse model

PURPOSE: Obstructive sleep apnea (OSA) is associated with renal impairs. As a novel pathophysiological hallmark of OSA, chronic intermittent hypoxia (CIH) enhances apoptosis and autophagy. The present study aims to evaluate the effect of telmisartan on CIH-induced kidney apoptosis and autophagy in a...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Bin, Cai, Jing-Huang, Yang, Yu-Yun, Zeng, Yi-Ming, Zeng, Hui-Qing, Wang, Miao, Cheng, Xiao, Luo, Xiongbiao, Ewurum, Henry Chidozie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418059/
https://www.ncbi.nlm.nih.gov/pubmed/30219962
http://dx.doi.org/10.1007/s11325-018-1720-9