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Timing constraints of action potential evoked Ca(2+) current and transmitter release at a central nerve terminal
The waveform of presynaptic action potentials (APs) regulates the magnitude of Ca(2+) currents (I(Ca)) and neurotransmitter release. However, how APs control the timing of synaptic transmission remains unclear. Using the calyx of Held synapse, we find that Na(+) and K(+) channels affect the timing b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418091/ https://www.ncbi.nlm.nih.gov/pubmed/30872753 http://dx.doi.org/10.1038/s41598-019-41120-5 |