Intratumor heterogeneity inferred from targeted deep sequencing as a prognostic indicator

Tumor genetic heterogeneity may underlie poor clinical outcomes because diverse subclones could be comprised of metastatic and drug resistant cells. Targeted deep sequencing has been used widely as a diagnostic tool to identify actionable mutations in cancer patients. In this study, we evaluated the...

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Detalles Bibliográficos
Autores principales: Oh, Bo Young, Shin, Hyun-Tae, Yun, Jae Won, Kim, Kyu-Tae, Kim, Jinho, Bae, Joon Seol, Cho, Yong Beom, Lee, Woo Yong, Yun, Seong Hyeon, Park, Yoon Ah, Park, Yeon Hee, Im, Young-Hyuck, Lee, Jeeyun, Joung, Je-Gun, Kim, Hee Cheol, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418103/
https://www.ncbi.nlm.nih.gov/pubmed/30872730
http://dx.doi.org/10.1038/s41598-019-41098-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418103/
https://www.ncbi.nlm.nih.gov/pubmed/30872730
http://dx.doi.org/10.1038/s41598-019-41098-0

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