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The Post-Synaptic Function of Brca2
Homologous Recombination (HR) is a high-fidelity process with a range of biologic functions from generation of genetic diversity to repair of DNA double-strand breaks (DSBs). In mammalian cells, BRCA2 facilitates the polymerization of RAD51 onto ssDNA to form a presynaptic nucleoprotein filament. Th...
Autores principales: | Wang, Charles X., Jimenez-Sainz, Judit, Jensen, Ryan B., Mazin, Alexander V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418147/ https://www.ncbi.nlm.nih.gov/pubmed/30872704 http://dx.doi.org/10.1038/s41598-019-41054-y |
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