Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis

Autosomal dominant polycystic kidney disease (ADPKD) is the most common renal genetic disorder, however it still lacks a cure. The discovery of new therapies heavily depends on understanding key signalling pathways that lead to ADPKD. The JAnus Kinase and Signal Transducers and Activators of Transcr...

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Detalles Bibliográficos
Autores principales: Patera, Foteini, Cudzich-Madry, Alex, Huang, Zhi, Fragiadaki, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418191/
https://www.ncbi.nlm.nih.gov/pubmed/30872773
http://dx.doi.org/10.1038/s41598-019-41106-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418191/
https://www.ncbi.nlm.nih.gov/pubmed/30872773
http://dx.doi.org/10.1038/s41598-019-41106-3

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