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TNFα is responsible for the canonical offspring number-size trade-off

There is a canonical life-history trade-off between quantity and quality of offspring, but molecular determinants for this are unknown. Here, we show that knockout of tumor necrosis factor (TNF-KO) in mice switched a relation between the number and size of developing embryos from expectedly negative...

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Detalles Bibliográficos
Autores principales: Maslennikova, S. O., Gerlinskaya, L. A., Kontsevaya, G. V., Anisimova, M. V., Nedospasov, S. A., Feofanova, N. A., Moshkin, M. P., Moshkin, Y. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418207/
https://www.ncbi.nlm.nih.gov/pubmed/30872598
http://dx.doi.org/10.1038/s41598-019-38844-9