Changes in the asymmetric distribution of cholesterol in the plasma membrane influence streptolysin O pore formation

ATP-binding cassette A1 (ABCA1) plays a key role in generating high-density lipoprotein (HDL) and preventing atherosclerosis. ABCA1 exports cholesterol and phospholipid to apolipoprotein A-I (apoA-I) in serum to generate HDL. We found that streptolysin O (SLO), a cholesterol-dependent pore-forming t...

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Detalles Bibliográficos
Autores principales: Ogasawara, Fumihiko, Kano, Fumi, Murata, Masayuki, Kimura, Yasuhisa, Kioka, Noriyuki, Ueda, Kazumitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418215/
https://www.ncbi.nlm.nih.gov/pubmed/30872611
http://dx.doi.org/10.1038/s41598-019-39973-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418215/
https://www.ncbi.nlm.nih.gov/pubmed/30872611
http://dx.doi.org/10.1038/s41598-019-39973-x

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