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Organoid-derived C-Kit(+)/SSEA4(−) human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents

Stem cell therapy may replace lost photoreceptors and preserve residual photoreceptors during retinal degeneration (RD). Unfortunately, the degenerative microenvironment compromises the fate of grafted cells, demanding supplementary strategies for microenvironment regulation. Donor cells with both p...

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Detalles Bibliográficos
Autores principales: Zou, Ting, Gao, Lixiong, Zeng, Yuxiao, Li, Qiyou, Li, Yijian, Chen, Siyu, Hu, Xisu, Chen, Xi, Fu, Caiyun, Xu, Haiwei, Yin, Zheng Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418223/
https://www.ncbi.nlm.nih.gov/pubmed/30872578
http://dx.doi.org/10.1038/s41467-019-08961-0