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Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy

Extracellular vesicles (EVs) that are derived from mesenchymal stromal cells (MSCs) have been shown to reprogram injured cells by activating regenerative processes. We herein investigate the potential therapeutic effect of EVs, shed by human bone marrow MSCs and by human liver stem-like cells (HLSCs...

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Detalles Bibliográficos
Autores principales: Grange, Cristina, Tritta, Stefania, Tapparo, Marta, Cedrino, Massimo, Tetta, Ciro, Camussi, Giovanni, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418239/
https://www.ncbi.nlm.nih.gov/pubmed/30872726
http://dx.doi.org/10.1038/s41598-019-41100-9