High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

We previously used RNA-seq to identify chemicals whose effects on neuronal gene expression mimicked transcriptional signatures of autism, aging, and neurodegeneration. However, this approach was costly and time consuming, which limited our study to testing a single chemical concentration on mixed se...

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Detalles Bibliográficos
Autores principales: Simon, Jeremy M., Paranjape, Smita R., Wolter, Justin M., Salazar, Gabriela, Zylka, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418307/
https://www.ncbi.nlm.nih.gov/pubmed/30872602
http://dx.doi.org/10.1038/s41598-019-39016-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418307/
https://www.ncbi.nlm.nih.gov/pubmed/30872602
http://dx.doi.org/10.1038/s41598-019-39016-5

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