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High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq
We previously used RNA-seq to identify chemicals whose effects on neuronal gene expression mimicked transcriptional signatures of autism, aging, and neurodegeneration. However, this approach was costly and time consuming, which limited our study to testing a single chemical concentration on mixed se...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418307/ https://www.ncbi.nlm.nih.gov/pubmed/30872602 http://dx.doi.org/10.1038/s41598-019-39016-5 |