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Human cytomegalovirus hijacks the autophagic machinery and LC3 homologs in order to optimize cytoplasmic envelopment of mature infectious particles

During its life cycle, Human cytomegalovirus (HCMV) tightly modulates autophagy, a vesicular pathway allowing degradation and recycling of cellular components. To study the interplay between autophagy and the viral life cycle, we established various autophagy-deficient human fibroblastic cell lines....

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Detalles Bibliográficos
Autores principales: Taisne, Clémence, Lussignol, Marion, Hernandez, Eva, Moris, Arnaud, Mouna, Lina, Esclatine, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418312/
https://www.ncbi.nlm.nih.gov/pubmed/30872707
http://dx.doi.org/10.1038/s41598-019-41029-z