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The promising role of PAX1 (aliases: HUP48, OFC2) gene methylation in cancer screening

BACKGROUND: Paired‐box gene 1 (PAX1), a member of the PAX family, plays a role in pattern formation during embryogenesis, and might be essential for development of the vertebral column. METHODS: PAX1 is silenced by methylation in several cancers and is considered a tumor suppressor gene. Our previou...

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Detalles Bibliográficos
Autores principales: Fang, Chao, Wang, Sai‐Ying, Liou, Yu‐Ligh, Chen, Ming‐Hua, Ouyang, Wen, Duan, Kai‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418350/
https://www.ncbi.nlm.nih.gov/pubmed/30636379
http://dx.doi.org/10.1002/mgg3.506