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The Effect of Fluid Shear Stress on the In Vitro Release Kinetics of Sirolimus from PLGA Films

Drug-carrying coatings of stents implanted in blood vessels are exposed to various blood flows. This study investigated the effect of fluid shear stress on the in vitro release kinetics of sirolimus from poly(lactic-co-glycolic acid) (PLGA) films. The homemade parallel plate flow chamber was used to...

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Detalles Bibliográficos
Autores principales: Zheng, Quan, Chu, Zhaowei, Li, Xiaoming, Kang, Hongyan, Yang, Xiao, Fan, Yubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418679/
https://www.ncbi.nlm.nih.gov/pubmed/30965925
http://dx.doi.org/10.3390/polym9110618