Multi‐omics identify xanthine as a pro‐survival metabolite for nematodes with mitochondrial dysfunction

Aberrant mitochondrial function contributes to the pathogenesis of various metabolic and chronic disorders. Inhibition of insulin/IGF‐1 signaling (IIS) represents a promising avenue for the treatment of mitochondrial diseases, although many of the molecular mechanisms underlying this beneficial effe...

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Detalles Bibliográficos
Autores principales: Gioran, Anna, Piazzesi, Antonia, Bertan, Fabio, Schroer, Jonas, Wischhof, Lena, Nicotera, Pierluigi, Bano, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418696/
https://www.ncbi.nlm.nih.gov/pubmed/30796049
http://dx.doi.org/10.15252/embj.201899558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418696/
https://www.ncbi.nlm.nih.gov/pubmed/30796049
http://dx.doi.org/10.15252/embj.201899558

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