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Design of a Versatile pH-Responsive Hydrogel for Potential Oral Delivery of Gastric-Sensitive Bioactives

A pH-responsive hydrogel system was prepared by free radical polymerization of acrylamide and methyl acrylic acid in the presence of N-N′-methylene bisacrylamide. Sodium bicarbonate was further applied as a blowing agent, which afforded a porous hydrogel structure. The hydrogel system achieved a con...

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Detalles Bibliográficos
Autores principales: Hibbins, Angus R., Kumar, Pradeep, Choonara, Yahya E., Kondiah, Pierre P. D., Marimuthu, Thashree, du Toit, Lisa C., Pillay, Viness
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418787/
https://www.ncbi.nlm.nih.gov/pubmed/30965777
http://dx.doi.org/10.3390/polym9100474