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Preformulation Studies of Furosemide-Loaded Electrospun Nanofibrous Systems for Buccal Administration

Furosemide loaded electrospun fibers were prepared for buccal administration, with the aim of improving the oral bioavailability of the poorly soluble and permeable crystalline drug, which can be achieved by the increased solubility and by the circumvention of the intensive first pass metabolism. Th...

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Detalles Bibliográficos
Autores principales: Kovács, Andrea, Démuth, Balázs, Meskó, Andrea, Zelkó, Romána
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418805/
https://www.ncbi.nlm.nih.gov/pubmed/30965943
http://dx.doi.org/10.3390/polym9120643