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Thiolated Chitosan Masked Polymeric Microspheres with Incorporated Mesocellular Silica Foam (MCF) for Intranasal Delivery of Paliperidone

In this study, mesocellular silica foam (MCF) was used to encapsulate paliperidone, an antipsychotic drug used in patients suffering from bipolar disorder. MCF with the drug adsorbed was further encapsulated into poly(lactic acid) (PLA) and poly(lactide-co-glycolide) (PLGA) 75/25 w/w microspheres an...

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Detalles Bibliográficos
Autores principales: Nanaki, Stavroula, Tseklima, Maria, Christodoulou, Evi, Triantafyllidis, Konstantinos, Kostoglou, Margaritis, Bikiaris, Dimitrios N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418893/
https://www.ncbi.nlm.nih.gov/pubmed/30965919
http://dx.doi.org/10.3390/polym9110617