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Noncovalent Complexation of Amphotericin B with Poly(β-Amino Ester) Derivates for Treatment of C. Neoformans Infection

Our goal was to improve treatment outcomes for C. neoformans infection by designing nanocarriers that enhance drug-encapsulating capacity and stability. Thus, a noncovalent complex of methoxy poly(ethylene glycol)-poly(lactide)-poly(β-amino ester) (MPEG-PLA-PAE) and amphotericin B (AMB) was develope...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Peng, Li, Liao, Guojian, Chen, Zhangbao, Li, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419036/
https://www.ncbi.nlm.nih.gov/pubmed/30960254
http://dx.doi.org/10.3390/polym11020270